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Key Points

Osmotic changes in culture media and IVF outcomes - Course ID:119 -
SEP192 [775]
This course describes publications exploring the implications of osmotic changes can have on IVF outcomes.
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Primary Topic 192
6/1/2021 - [Last Updated:19/2/2021]
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Created 6/1/2021
Updated 19/2/2021
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21 Key Topics
20 Questions
7 References
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List of Key Points FILTER: Key Point Background Comments
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There are 20 questions for subscribers to complete.

References related to Osmotic changes -[6] [Ref=7]
Swain JE, Cabrera L, Xu X, Smith GD. Microdrop preparation factors influence culture-media osmolality, which can impair mouse embryo preimplantation development. Reprod Biomed Online. 2012,24(2):142-147. doi:10.1016/j.rbmo.2011.10.008 ID:2507
Year:2012, DOI:10.1016/j.rbmo.2011.10.008 401 8573 2012 Last edited on
Yumoto K, Iwata K, Sugishima M, et al. Unstable osmolality of microdrops cultured in non-humidified incubators. J Assist Reprod Genet. 2019,36(8):1571-1577. doi:10.1007/s10815-019-01515-9 ID:2508
Year:2019, DOI:10.1007/s10815-019-01515-9 402 8573 2019 Last edited on
Chi HJ, Park JS, Yoo CS, Kwak SJ, Son HJ, Kim SG, Sim CH, Lee KH, Koo DB. Effect of evaporation-induced osmotic changes in culture media in a dry-type incubator on clinical outcomes in in vitro fertilization-embryo transfer cycles. Clin Exp Reprod Med. 2020 Nov 23. ID:2927
Year:2020, DOI:10.5653/cerm.2020.03552 399 8774 2020 Last edited on 24/11/2020
Fawzy M, AbdelRahman MY, Zidan MH, Abdel Hafez FF, Abdelghafar H, Al-Inany H, Bedaiwy MA. Humid versus dry incubator: a prospective, randomized, controlled trial. Fertil Steril. 2017 Aug,108(2):277-283. doi: 10.1016/j.fertnstert.2017.05.036 ID:2928
Year:2017, DOI:10.1016/j.fertnstert.2017.05.036 400 0 2017 Last edited on 24/11/2020
Boumerdassi Y, Huet S, Millin M, Sarandi S, Smires BB, Sifer C. Impact du type d’incubateur (sec versus à atmosphère humidifiée) sur l’osmolalité des milieux de culture embryonnaire [Impact of the type of incubator (non-humidified versus humidified) on embryo culture media osmolality.]. Gynecol Obstet Fertil Senol. 2020 Dec 11:S2468-7189(20)30351-2. French. doi: 10.1016/j.gofs.2020.12.005 ID:2978
Year:2020, DOI:10.1016/j.gofs.2020.12.005 0 0 2020 Last edited on 17/12/2020
Mestres E, García-Jiménez M, Casals A, Cohen J, Acacio M, Villamar A, Matia-Algué Q, Calderón G, Costa-Borges N. Factors of the human embryo culture system that may affect media evaporation and osmolality. Hum Reprod. 2021 Jan 17:deaa370. doi: 10.1093/humrep/deaa370 ID:3083
Year:20201, DOI:10.1093/humrep/deaa370 0 8852 20201 Last edited on 19/1/2021
Steven F Mullen, Toward a predictive theoretical model for osmolality rise with non-humidified incubation: a randomized, multivariate response-surface study, Human Reproduction, 2021,, deab015, ID:3177
Year:2021, DOI:10.1093/humrep/deab015 0 0 2021 Last edited on 19/2/2021

Additional References related to Osmotic changes - [1]

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