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Key Points

niPGT-A - non-invasive preimplantation genetic testing+ - Course ID:172 -
SEP82 [865]
Non-invasive preimplantation genetic testing involves testing the spent culture medium that blastocysts were culture in for the presence of aneupolidy. Some doubt exists over whether such technology can replace trophectoderm biopsy.
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Primary Topic 82
23/3/2021 - [Last Updated:23/3/2021]
Cell free DNA , cfDNA , trophectoderm , aneuploidy , niPGT-A ,
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Created 23/3/2021
Updated 23/3/2021
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11 Key Topics
3 Questions
3 References
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References related to niPGT-A - non-invasive preimplantation genetic tes -[2] [Ref=3]
Shitara A, Takahashi K, Goto M, Takahashi H, Iwasawa T, Onodera Y, Makino K, Miura H, Shirasawa H, Sato W, Kumazawa Y, Terada Y. Cell-free DNA in spent culture medium effectively reflects the chromosomal status of embryos following culturing beyond implantation compared to trophectoderm biopsy. PLoS One. 2021 Feb 11,16(2):e0246438. doi: 10.1371/journal.pone.0246438 ID:3194
Year:2021, DOI:10.1371/journal.pone.0246438 0 8887 2021 Last edited on 25/2/2021
Babariya D, Leaver M, Wells D. Divining the genetic status of embryos: consult the medium? Fertil Steril. 2019 Sep,112(3):471-473. doi: 10.1016/j.fertnstert.2019.06.012 ID:3212
Year:2019, DOI:10.1016/j.fertnstert.2019.06.012 0 0 2019 Last edited on 16/3/2021
Hanson BM, Tao X, Hong KH, Comito CE, Pangasnan R, Seli E, Jalas C, Scott RT Jr. Noninvasive preimplantation genetic testing for aneuploidy exhibits high rates of deoxyribonucleic acid amplification failure and poor correlation with results obtained using trophectoderm biopsy. Fertil Steril. 2021 Mar 18:S0015-0282(21)00050-9. doi: 10.1016/j.fertnstert.2021.01.028 ID:3229
Year:2021, DOI:10.1016/j.fertnstert.2021.01.028 0 8902 2021 Last edited on 23/3/2021

Additional References related to niPGT-A - non-invasive preimplantation genetic tes - [1]

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