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Key Points

Reproducibility of trophectoderm biopsies+ - Course ID:81 -
SEP157+ [818]
Explores publications that have looked at the reproducibility of PGT-A biopsy. In particular the impact of mosaicism on the validiity of biopsy material.
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Primary Topic 157
7/1/2021 - [Last Updated:16/3/2021]
Cell free DNA , niPGT-A , PGT-A , aneuploidy , Self-correction ,
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Activity Date
Created 7/1/2021
Updated 16/3/2021
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20 Key Topics
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4 References
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References related to Reproducibility of trophectoderm biopsies -[3] [Ref=4]
Bolton, H., Graham, S., Van der Aa, N. et al. Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential. Nat Commun 7, 11165 (2016). ID:2714
Year:0, DOI:10.1038/ncomms11165 0 0 Last edited on
Orvieto R. The reproducibility of trophectoderm biopsies - The chaos behind preimplantation genetic testing for aneuploidy [published online ahead of print, 2020 Sep 14]. Eur J Obstet Gynecol Reprod Biol. 2020,254:57-58. doi:10.1016/j.ejogrb.2020.07.052 ID:2767
Year:0, DOI:10.1016/j.ejogrb.2020.07.052 0 8688 Last edited on
Sachdev NM, McCulloh DH, Kramer Y, Keefe D, Grifo JA. The reproducibility of trophectoderm biopsies in euploid, aneuploid, and mosaic embryos using independently verified next-generation sequencing (NGS): a pilot study. J Assist Reprod Genet. 2020,37(3):559-571. doi:10.1007/s10815-020-01720-x ID:2768
Year:0, DOI:10.1007/s10815-020-01720-x 0 8689 Last edited on
Orvieto R, Shimon C, Rienstein S, Jonish-Grossman A, Shani H, Aizer A. Do human embryos have the ability of self-correction? Reprod Biol Endocrinol. 2020 Oct 6,18(1):98. doi: 10.1186/s12958-020-00650-8 ID:2819
Year:0, DOI:10.1186/s12958-020-00650-8 0 8720 Last edited on

Additional References related to Reproducibility of trophectoderm biopsies - [1]

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