Most differences in DNA binding compounds found at birth in children conceived by IVF not seen in early childhood 
Compared to newborns conceived traditionally, newborns conceived through in vitro fertilization (IVF) are more likely to have certain chemical modifications to their DNA, according to a new study. The changes involve DNA methylation - the binding of compounds known as methyl groups to DNA - which can alter gene activity. Only one of the modifications was seen by the time the children were 9 years old.
Two subsequent seminal productions: a good strategy to treat very severe oligoasthenoteratozoospermic (OAT) infertile couples 
the results show that a short abstinence in severe OAT patients allows us to obtain sperm with better motility. The request for a second semen sample in couples with extreme semen parameters is a valid and simple strategy that helps to achieve the same probability of pregnancy compared to a Control Group. Furthermore, it allows us to utilize fresh sperms avoiding the need to resort to cryopreserved reserves or testicular surgery.
Male fertility: how everyday chemicals are destroying sperm counts in humans and animals 
Within just a few generations, human sperm counts may decline to levels below those considered adequate for fertility. That’s the alarming claim made in epidemiologist Shanna Swan’s new book, “Countdown”, which assembles a raft of evidence to show that the sperm count of western men has plunged by over 50% in less than 40 years
HIRA contributes to zygote formation in mice and is implicated in human 1PN zygote phenotype 
We then studied human 1PN zygotes and found that the HIRA complex was absent in 1PN zygotes that lacked the male pronucleus. This shows that the role of the HIRA complex in male pronucleus formation potentially has coherence from mice to humans.
The morphokinetic signature of mosaic embryos: evidence in support of their own genetic identity 
Conclusion(s): Morphokinetic timing of mosaic embryos overlaps with that of euploid and aneuploid embryos, which may reflect their unique genetic and developmental identity. Although this suggests mosaic embryos are not simply a misdiagnosis by-product, further studies are needed to reveal the true identity of this particular type of embryo.
Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcome 
Here we provide a complete summary of the major achievements in human implantation research supplied by omics approaches, highlighting their potential to improve reproductive outcomes while fully elucidating the implantation mechanism.
Non-invasive molecular assessment of human embryo development and implantation potential 
More importantly, hCGβ: detection was able to discriminate apparently morphologically identical viable embryos. This work brings an objective dimension to embryo selection, which could overcome the major limitations of morphology-based embryo selection for implantation.
SESSION 47: THE INVISIBLE MALE. International IVF Initiative 
“When ICSI killed Andrology” Professor Allan Pacey, "The Sixth Vital Sign: What Our Sperm Are Trying To Tell Us?" Professor Michael Eisenberg,
"The Male Reproductive Health Initiative" Professor Chris Barratt
Embryo morphokinetic score is associated with biomarkers of developmental competence and implantation 
Our data suggest that morphokinetic algorithms that predict development to blastocyst stage, in fact, also identify embryos with molecular and cellular profiles more consistent with developmental functions.
Clinical efficacy of hyaluronate-containing embryo transfer medium in IVF/ICSI treatment cycles: a cohort study 
The use of embryo transfer (ET) medium rich in HA improves LBE (a singleton or twin live birth) regardless of the duration of exposure evaluated in this study, but does not alter gestation or birthweight (BW).
Using outcome data from one thousand mosaic embryo transfers to formulate an embryo ranking system for clinical use 
This compiled analysis revealed traits of mosaicism identified with preimplantation genetic testing for aneuploidy that affected outcomes in a statistically significant manner, enabling the formulation of an evidence-based prioritization scheme for mosaic embryos in the clinic.
Microbial contamination in assisted reproductive technology: source, prevalence, and cost 
In conclusion, we urge clinics to more rigorously identify, register, and report contamination occurrences, and highlight the role of the study of the microbiome to improve overall results and safety of assisted reproduction.
Embryo biosensing by uterine natural killer cells determines endometrial fate decisions at implantation 
Killing of senescent decidual cells by uNK cells was also inhibited upon exposure to medium conditioned by IVF embryos that failed to implant, but not successful embryos. Embryo‐:::mediated inhibition of uNK cell activity was reversed by recombinant hyaluronidase 2 (HYAL2), which hydrolyses HMWHA. We further report a correlation between the levels of HYAL2 secretion by human blastocysts, morphological scores, and implantation potential. Take
Patient willingness, preferences and decision-making about planning for three complete cycles of IVF/ICSI treatment 
The majority of patients seem to value the opportunity to plan for multiple cycles of treatment while acknowledging both possible challenges and benefits of doing so and decisions that might need to be made in advance.