List of Recent Publications. There are 20 links to this search
Occupational health issues experienced by UK embryologists: informing improvements in clinical reproductive science practice 
Assessment of the evidence base for these work-related ill-health conditions explored contributory and ameliorating factors, which enabled a series of evidence-based recommendations to be formulated via the adoption of a GRADE-based framework.
A comparison of embryo culture strategies for women of advanced age with four or fewer available D3 embryos: a single centre retrospective analysis of 
In patients with blastocyst culture, the clinical conditions of those who had a successful outcome were better than those who failed. Blastocyst culture and transfer can significantly increase pregnancy rate per embryo transfer cycle and may be appropriate in some older patients with a good clinical prognosis.
Factors of the human embryo culture system that may affect media evaporation and osmolality 
Incubator humidity, the volume of mineral oil, the type of culture media and the design of time-lapse dishes have been identified as important parameters that can cause an impact on media evaporation and consequently osmolality during culture.
Clinical Outcomes Deriving from Transfer of Blastocysts Developed in Day 7: a Systematic Review and Meta-Analysis of Frozen-Thawed IVF Cycles 
This study shows an association between delayed blastulation and a poorer prognosis in terms of euploid rate and pregnancy outcomes following frozen-thawed transfers. On the other hand, the results do not support the discharge of slow-blastulation embryos.
Possibility of live birth in patients with low serum β:-hCG 14 :days after blastocyst transfer 
Initially low serum β:-hCG levels 14 :days after frozen blastocyst transfer indicated minimal chances of live birth. For patients having an initial β:-hCG > :58.8 mIU/ml, luteal phase support should continue.
Association between blastocyst morphology and maternal first trimester serum markers in ongoing pregnancies obtained after single fresh blastocyst tra 
Our study concluded that first trimester serum markers were not associated with blastocyst morphological characteristics. Although this needs further confirmation, this suggests that blastocyst morphology would not have an impact on placentation. Therefore, these findings are reassuring for couples undergoing IVF and blastocyst transfer.
Blastocyst morphology has no relationship with serum bhCG levels and live birth rates once pregnant 
Once the patient conceives after IVF with single blastocyst, none of the morphological parameters have a strong impact on the day16 serum level of β:::-hCG. Among women who conceived, blastocyst grade and stage were not associated with live births.
Intraovarian insertion of autologous platelet growth factors as cell-free concentrate: Fertility recovery and first unassisted conception with term de 
This is the first description of intraovarian injection of enriched platelet-derived growth factors followed by unassisted pregnancy and live birth. As a refinement of conventional ovarian platelet-rich plasma therapy, this procedure may be particularly valuable for refractory cases where prognosis for pregnancy appears especially bleak
Perspective: One-Cell and Cleavage-Stage Mouse Embryos Thrive in Hyperosmotic Oviductal Fluid Through Expression of a Glycine Neurotransmitter Transpo 
The glycine concentration in oviductal fluid can, however, rescue development in hypertonic media, so physiological conditions in vivo and in vitro likely work together to foster embryo well-being. Glycine acts on one-cell and cleavage-stage mouse embryos through the glycine-gated chloride channel, GLRA4, and uptake via the glycine neurotransmitter transporter
Effect of ovarian stimulation on embryo aneuploidy and mosaicism rate 
However, the duration of COS showed association with the appearance of aneuploidy, suggesting that faster recruitment could be deleterious for those reassuming meiosis, yielding more abnormal karyotype.
Assisted oocyte activation effects on the morphokinetic pattern of derived embryos 
We conclude that ionomycin mediated AOA does not seem to affect the morphokinetic pattern of preimplantation embryo development, despite the alterations found in tPB2 and t3, which could directly reflect the use of a Ca2+ ionophore as a transient and quick non-physiologic increase of free intracytoplasmic Ca2+.
Social egg freezing and donation: waste not, want not 
We propose a possible pathway to address these dual realities. The donation of oocytes originally stored in the context of AGE banking, with appropriate compensatory mechanisms, would ameliorate AGE banking concerns, while simultaneously improving the supply of donor oocytes. This proposed arrangement will result in tangible benefits for prospective donors, recipients and society at large.
Six-year follow-up of children born from vitrified oocytes 
This is the first follow-up report of children born from vitrified-warmed oocytes followed by ICSI. The data suggested that the responses from the study participants on the mental and physical development of children were comparable to the data reported by the government, although more responses from patients should be collected to allow further study.
Seminal oxidation-reduction potential as a possible indicator of impaired sperm parameters in Turkish population 
Oxidative stress determined by MiOXSYS system was found to be related to reduced sperm parameters in Turkish population, which may be used as an indicator of poor sperm parameters and a support to routine semen analysis. In addition, recommended reference value was found to be reliable in distinguishing normal from impaired semen parameters.
International IVF Initiative-Hosts Dr. Denny Sakkas-AI Driven Innovations in Automated Semen Analysis Building A Better Mousetrap.
Dr. Ashok Agarwal-“Nature doesn’t use a centrifuge: Microfluidics and the future of sperm preparation” Matt Feldman -Sperm DNA Fragmentation – Unlocking the secrets for the ART professionalDr. Sandro Esteves
Semen Analysis/Microfluidics/Sperm DNA Fragmentation/
'Your hopes can run away with your realistic expectations': a qualitative study of women and men's decision-making when undergoing multiple cycles of 
Factors contributing to the decision included external factors, such as their doctor's guidance, success rates, the outcomes of previous cycles and anecdotal stories of success, as well as emotional and cognitive drivers, including perception of success, hope and fear of regret.
Experiences of women undergoing infertility treatment from embryo transfer until pregnancy test and their conceptualization of their embryo 
In this study, it was determined that women had intense physical and emotional experiences during the waiting period after ET and their daily lives were affected. It was also understood that the embryo means "baby/child/son/daughter" to them and that they establish a close bond with their embryos.