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Orvieto R, Aizer A, Gleicher N. Is there still a rationale for non-invasive PGT-A by analysis of cell-free DNA released by human embryos into culture medium? Hum Reprod. 2021 Mar 4:deab042. doi: 10.1093/humrep/deab042
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  Is there still a rationale for non-invasive PGT-A by analysis of cell-free DNA released by human embryos into culture medium?
  High rates of false-positive diagnoses of human embryos often lead to non-use and/or disposal of embryos with entirely normal pregnancy potential. Before adopting yet another round of unvalidated PGT-A as a routine adjunct to IVF, we here present facts that deserve to be considered.
 
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KeyWords tagged to this link. self-correction/PGT-A/trophectoderm biospy/cfDNA/niPGT-A/
self-correction PubMed  
PGT-A PubMed  
trophectoderm biospy PubMed  
cfDNA PubMed  
niPGT-A PubMed  
         
 
 
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  Key Topic Key Point  
1597 Background Human embr .. you need to be logged in to read these questions.
1598 Blastocysts expelled cell debris The author .. you need to be logged in to read these questions.
1599 Expelled aneuploid debris The author .. you need to be logged in to read these questions.
1600 Impact of self correction The author .. you need to be logged in to read these questions.
1601 Conclusion The author .. you need to be logged in to read these questions.
 
 
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